Cinnamic acids and derivatives
Apexbio Technology LLC Entacapone 130929-57-6 100mg
Entacapone (CAS 130929-57-6) is a selective second-generation inhibitor of catechol-O-methyltransferase (COMT) It demonstrates potent inhibition of total COMT in mouse liver with reported IC50 and Ki values of 20 1 nM and 10 7 nM respectively In rat models IC50 values for soluble COMT and membrane-bound COMT are 14 3 nM and 73 3 nM Entacapone is primarily utilized in research as an adjunct to levodopa and dopa decarboxylase inhibitor regimens in Parkinson s disease studies given its ability to suppress the formation of 3-O-methyldopa thereby enhancing levodopa bioavailability and prolonging its pharmacological effect
Waters Corp Ion Chamber, CI, MS System, Replacement Part
This replacement Ion Chamber is designed for Chemical Ionization (CI) applications within an MS System. It functions as a critical component, used specifically on the Xevo TQ-GC system.
- Categorized as a replacement parts kit
- Mechanical type
- Used in MS (Mass Spectrometry) systems
- Replaced as required
Selleck Chemical LLC Ferulic acid methyl ester S5451-25mg
Ferulic acid methyl ester (Methyl Ferulate Methyl 4 -hydroxy-3 -methoxycinnamate) is a lipophilic derivative of ferulic acid which is a hydroxycinnamic acid that is abundant in plants It shows the strongest antioxidant activity and can protect against inflammation and cancer
Selleck Chemical LLC Ferulic Acid S2300-10mM/1mL
Ferulic Acid (Fumalic) is a hydroxycinnamic acid and a type of organic compound found in the Ferula assafoetida L or Ligusticum chuanxiong Ferulic acid is a novel fibroblast growth factor receptor (FGFR) inhibitor with IC50s of 3 78 M and 12 5 M for FGFR1 and FGFR2 respectively
Medchemexpress LLC p-Coumaric acid (standard) | 501-98-4 | 164.16 | 100 MG
p-Coumaric acid (Standard) is the analytical standard of p-Coumaric acid, intended for research and analytical applications. It is an isomer of cinnamic acid with oral activity. p-Coumaric acid inhibits cell proliferation, promotes apoptosis, and exhibits antibacterial, anti-inflammatory, antioxidant, and anti-tumor activities.
- Analytical standard for research and analytical applications
- Inhibits cell proliferation and promotes apoptosis
- Exhibits antibacterial, anti-inflammatory, antioxidant, and anti-tumor activities
- Used as a reference standard in qualitative, quantitative, and methodological research experiments
- Suitable for HPLC, GC, and MS applications
Medchemexpress LLC Cinnamic acid | 621-82-9 | MFCD00004369 | 148.16 | 1 G
Cinnamic acid has potential use in cancer intervention, exhibiting IC50s of 1-4.5 mM in glioblastoma, melanoma, prostate, and lung carcinoma cells. In addition to inhibiting tumor-cell proliferation, Cinnamic acid induces morphological changes consistent with melanocyte differentiation. Treatment with Cinnamic acid also leads to a dose-dependent loss of invasive capacity in various tumor lines.
- Endogenous metabolite
- Potential use in cancer intervention
- Exhibits dose-dependent growth inhibition in various tumor cells
- Induces morphological changes consistent with melanocyte differentiation
- Causes dose-dependent loss of invasive capacity in tumor lines
- Purity: 99.98%
- Appearance: Solid
- Color: White to off-white
- Initial source: Microorganisms
- Storage: powder at -20°C for 3 years, 4°C for 2 years; in solvent at -80°C for 2 years, -20°C for 1 year
Apexbio Technology LLC Entacapone 130929-57-6 10mg
Entacapone (CAS 130929-57-6) is a selective second-generation inhibitor of catechol-O-methyltransferase (COMT) It demonstrates potent inhibition of total COMT in mouse liver with reported IC50 and Ki values of 20 1 nM and 10 7 nM respectively In rat models IC50 values for soluble COMT and membrane-bound COMT are 14 3 nM and 73 3 nM Entacapone is primarily utilized in research as an adjunct to levodopa and dopa decarboxylase inhibitor regimens in Parkinson s disease studies given its ability to suppress the formation of 3-O-methyldopa thereby enhancing levodopa bioavailability and prolonging its pharmacological effect
Medchemexpress LLC Ferulic acid sodium | 24276-84-4 | 99.9% | 216.17 | 10 MM * 1 ML
Ferulic acid sodium | 24276-84-4 | 99.9% | 216.17 | 10 MM * 1 ML
Medchemexpress LLC Curcumin 5-8 | 890984-26-6 | 98.6% | 339.39 | 5 MG
Curcumin 5-8 is a potent and orally active natural curcumin analog. It inhibits lipid droplet formation, increases autophagy, and inhibits apoptosis. It also improves insulin resistance and insulin sensitivity.
- Inhibits lipid droplet formation.
- Increases autophagy.
- Inhibits apoptosis.
- Improves insulin resistance.
- Improves insulin sensitivity.
eMolecules 871126-24-8 | 2-(3'-Fluorobenzyloxy)phenylboronic acid | Combi-Blocks | MFCD07784392 | 246.040 | C13H12BFO3 | 98.000 | OB(O)c1ccccc1OCc1cccc(F)c1 | 1g | 117525198
2-(3'-Fluorobenzyloxy)phenylboronic acid | Combi-Blocks | 871126-24-8 | MFCD07784392 | 246.040 | C13H12BFO3 | 98.000 | OB(O)c1ccccc1OCc1cccc(F)c1 | 1g | 117525198